In recent years, the Paleo Diet has received considerable attention as a means for improving overall health. The anecdotal evidence for patient improvement on a Paleo, or the more restrictive Autoimmune Paleo (AIP) diet, is abundant. What you hear less frequently is that some people experience negative effects, or a worsening of symptoms with a Paleo or AIP diet. It seems counterintuitive that eating a healthy diet high in cruciferous greens such as kale, cabbage, and broccoli, in combination with high quality proteins and fats, can make you feel worse. Why is that the case?